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KMID : 0378019820250090083
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New Medical Journal
1982 Volume.25 No. 9 p.83 ~ p.88
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The effect of Bezafibrate (Bezalip^(®)) on hyperlipidemia
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Abstract
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Hyperlipidemia increases the risk for atherosclerotic coronary heart diseaes and cerebrovascular disease.
Treatment of hyperlipidemia includes primarily diet control, maintenance of ideal body weight, physical exercise and reduction of smoking etc, but so frequently this lipid disorder is normalized unsatisfactorily with these conservative methods. We controlled a study on the effect of Bezafibrate(Bezalip®) on patients with hyperlipidemia who visited Busan National University Hospital. 200mg of Bezalip® was administered 3 times a day for 4 weeks, and the result as follows:
1. Serum cholesterol and triglyceride were reduced from 271.0mg% to 227.27mg% (p< 0.001) and 246/ lmg% to 149.Omg% (p<0. 001) respectively and serum HDL-choesterol increased from 44.08mg% to 58.76mg% (p<0. 01) after 4-week-treatment.
2. Percentile decrease in serum cholesterol and triglyceride were 16.13% and 39.46% respectively, and percentile elevation in serum HDL-choesterol was 33.33% after 4-weektreatment.
3. The effectiveness in serum cholesterol, triglyceride and HDL-cholesterol were 90.0%, 86.7% and 75.0% respectively.
4.. The undesirable effect of the drug was not found during this observation period.
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KEYWORD
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